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Current Research Investigations as of May 2008

Award PI Last Name Award Sponsor Name Project Title
COTMAN PHS - NIH Inst on Aging Alzheimer's Disease Research Center of the University of California Irvine
  Univ of WA National Alzheimer's Coordinating Center (NACC) Participant
  PHS - NIH Inst on Aging Brain Aging and Gene Expression Patterns Using Microarrays
  State of CA - H&W, Misc Agencies Alzheimer's Disease Research Center at The University of California Irvine
  The effort on this project is focused on clinical evaluation and characterization of research subjects in the ADRC.
 
CRAMER STEM CELL THERAPEUTICS CORP. (CANADA) Safety of Beta-Hcg + Erythropoeitin in Acute Stroke
  NORTHSTAR NEUROSCIENCE, INC (FRMLY VERTIS NEUROSCIENCE) Analysis of MRI Data From a Restorative Stroke Trial
  Rehabilitation Inst of Chicago Engineering for Neurologic Rehabilitation
  University of Florida BDNF Genotype, Cortical Plasticity and Recovery from Stroke
 
CRIBBS PHS - NIH Neurological Disorders & Stroke Combining AD Epitope Vaccine with Innate Immunity
  PHS-NIH Inst on Aging Multiple Approaches to Abeta Vaccination in Animal Models
  American Health Assistance Fdn CNS Delivery of Immunotherapy Using MSCs
  UC Mexus Selection of Potentially Therapeutic Single Chain Antibodies Directed Against N-Truncated Forms of Amyloid-Beta Peptide
  Centocor, A Johnson & Johnson Company Investigation of the Effect of Anti-Beta-Amyloid Antibodies on Cognitive Behavior in the 3xTg-AD Mouse Model of Alzheimer's Disease
 
DEMETRIOU National Multiple Sclerosis Soc Regulation of Spontaneous Autoimmune Demyelinating Disease by Mgat5 N-Glycns
   
FISHER PHS - NIH Neurological Disorders & Stroke Hemorheological Factors in Cerebral Ischemia
  Boehringer Ingelheim Effects Of Telmisartan (Micardis) and/or Dipyridamole On Brain Microvasulature In Vitro
 
HERMANOWICZ Teva Neuroscience Inc. A Multicenter, Double-Blind, Randomized Start, Placebo-Controlled, Parallel-Group Study to Assess Rasagiline as a Disease Modifying Therapy in Early Parkinson's Disease Subjects
  Valeant Pharmaceuticals Intl A to Z (Agonist to Zelapar)
  Allergan Inc A Multicenter Study Evaluating The Efficacy And Safety Of Botox (Botulinum Toxin Type A) Purified Neurotoxin Complex As a Headache Prophylaxis In Migraine Patients With 15 Or More Headache Days Per 4-Week Period In A 24-Week, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Phase Followed By A 32-Week Open Label Extension Phase
  Allergan Inc A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Single Treatment Cycle, Parallel Evaluation of the Safety, Efficacy and Immunogenicity of Two Formulations of BOTOX (Botulinum Toxin Type A) Purified Neurotoxin Complex (Formulation Nos. 9060X and 9525X), Followed by a Blinded Active Treatment Extnension of up to Two Additional Treatment Cycles in Patients with Cervical Dystonia
  Kyowa Pharmaceuticals Inc An Open-Label, Multicenter, Study of The Continued Safety of Istradefylline In Subjects With Parkinson's Disease Who Have Recently Completed One Year Of Treatment With Istradefylline
  Quintiles Transnatl Inc. A Multi-Center, Randomized, Double Blind, Placebo-Controlled, Parallel Group Study of the Efficacy, Safety and Tolerability of E2007 in Levodopa Treated Parkinson's Disease Patients with Motor Fluctuations
  Quintiles A Multi-centre, Open Label Extension Study to Evaluate the Long-Term Safety, Tolerability and Efficacy of E2007 as an Adjunctive Therapy in Levodopa Treated Parkinson's Disease Patients with Motor Fluctuations
  Inc Research, Inc (Raleigh, North Carolina) A Multi-Center, Placebo-Controlled, Double-Blind Trial to Examine the Safety & Efficacy of ACP-103 in the Treatment of Psychosis in Parkinson's Disease
  Inc Research, Inc (Raleigh, North Carolina) Prospective, Double-Blind, Placebo-Controlled, Randomized, Multi-Center Trial With a Double-Blind Parallel-Group Extension Period to Investigate the Efficacy and Safety of Different Doses of NT 201 in the Treatment of Cervical Dystonia.
  Novartis AG A Prospective, Multi-Center, Randomized, Open-Label Study with Blinded Raters to Evaluate the Effects of Immediate Versus Delayed Switch to Stalevo on Motor Function and Quality of Life in Patients with Parkinson's Diseases with End-of-Dose Wearing Off
 
KAWAS NIA/NIH Clinical and Pathological Studies in the Oldest Old - The 90+ Study
  NIA/NIH Alzheimer's Disease Research Center of UCI - Clinical evaluation and characterization of research subjects in the ADRC
  NCCAM/NIH Ginkgo Biloba Prevention Trial in Older Individuals (GEM Study)
  NIA/NIH Leukocyte-Derived Biomarkers as Predictors of Risk Progression in AD
 
MOZAFFAR Univ of AL at Birmingham Thymectomy in Non-Thymomatous MG Patients on Prednisone
  Insmed Inc A Placebo controlled, Randomized, Double-Blind Phase II Clinical Trial to Evaluate Tolerability, Safety and Efficacy Endpoints after Administration of Recombinant Human Insulin-Like Growth Factor-I/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 (rhIGFBP-3) for 24 Weeks in Adults with Myotonic Dystrophy Type I
  Phoenix Neurological Associates, Ltd Database of Immune-Mediated Neuropathy Treatment Outcomes
 
SCHREIBER Alzheimer's Assc Efficacy of Nicotinamide for the Treatment of Alzheimer's Disease
 
STARR PHS-NIH Deafness & Other Communication Disorders Hearing Deficit Due to Auditory Neuropathy
 
WEISS PHS-NIH Neurological Disorders & Stroke AMPA/Kainate Receptors, Free Radicals and Motor Neuron injury